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However, aging disrupts mitochondrial redox balance, leading to increased oxidative stress, sleep disturbances, and a heightened risk of neurodegenerative diseases like Alzheimers disease

(2003) Journal of Clinical Endocrinology & Metabolism n=120 Phase 2 double-blind trial of AOD 9604 5mg daily versus placebo in obese subjects measuring weight loss and lipid changes

Clinically, ketogenic or fasting-mimicking cycles reduce glucose and insulin, enrich -hydroxybutyrate, and enlarge the therapeutic index of chemo- and radiotherapy or immune checkpoint blockade 1,25,384,385,386,387